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  Home > 2016 Conference series > Protein misfolding in disease - Toxic aggregation-prone proteins in aging and age-related diseases: from structure to pathology and spreading

Protein misfolding in disease - Toxic aggregation-prone proteins in aging and age-related diseases: from structure to pathology and spreading

 French version

Roscoff (Brittany), France, September 12-16, 2016

 

Deadline for application: May 18, 2016

 

Chairperson: Luc BUÉE

Equipe Alzheimer & Tauopathies, Jean-Pierre Aubert research center, Université de Lille Faculté de Médecine - Pôle Recherche, 59045 Lille, France
Phone: +33 (0) 3 20 29 88 50
Email: luc.buee@inserm.fr

 

Vice-chairperson: Ellen NOLLEN

University of Groningen, European Res Instit for Biology of Ageing, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
Phone: +31 652 724 881
Email : e.a.a.nollen@umcg.nl

 

 

The conference will focus on protein misfolding in aging and diseases including Alzheimer's, Parkinson's, Huntington's and prion diseases. This meeting will follow on from the series of three previous meetings on protein misfolding and aggregation.

This time, we will center around proteostasis, misfolding, spreading and potential for therapies and diagnosis. It will include multidisciplinary talks such as protein chemistry and structure, brain imaging, cell biology and pathophysiology. The program will include talks in which the research utilized model organisms (from C. elegans to non-human primates) and also those focused on in vitro research.

Main discussions will include protein misfolding and clearance, nature of the toxic species, definition of "prion-like" transmission and propagation. We will open up on innovative therapeutic strategies and potential targets for diagnosis.


Invited speakers
(provisional titles)

 

BEZARD Erwan (Bordeaux, France)
Parkinson’s disease and spreading of alpha-synuclein aggregates

BRICE Alexis (Paris, France)
Experimental models of protein aggregates

BUÉE Luc (Lille, France)
From Tau trans-cellular transfer to prion-like propagation

BUKAU Bernd (Heidelberg, Germany)
Mechanisms of chaperone mediated protein disaggregation

CHECLER Frédéric (Valbonne, France)
Aggregation in Alzheimer’s disease: which pathological trigger beside Aß

CHETELAT Gaël (Caen, France)
A neuroimaging perspective of the role of connectivity and brain network in Alzheimer’s disease neurodegeneration topography and spreading

CICCHETTI Francesca (Québec, Canada)
Prion-like propagation of the mutant huntingtin gene product in Huntington's disease: implications for understanding the pathology and developing new treatment strategies

CLEVELAND Don (La Jolla, USA)
Gene silencing therapy for neurodegenerative disease: ALS, Huntington’s disease and beyond

DELATOUR Benoît (Paris, France)
Imaging in Alzheimer’s experimental models

DIAMOND Marc (Dallas, USA)
New insights into human tauopathy based on the prion model

GUILLOTEAU Denis (Tours, France)
Amyloid PET imaging

HANTRAYE Philippe (Fontenay-aux-Roses, France)
In vivo modelling and longitudinal monitoring of tauopathies in the living rat and non-human primate

JUCKER Mathias (Tuebingen, Germany)
From Aß seeds to Fluid disease biomarkers in mouse models of neurodegenerative diseases

KAGANOVICH Daniel (Jerusalem, Israël)
Intermediate filaments modulate protein folding quality control by binding to disordered proteins

KAMINSKI-SCHIERLE Gabriele (Cambridge, United Kingdom)
Molecular insight into Tau propagation and misfolding

LIPPENS Guy (Villeneuve d'Ascq, France)
NMR spectroscopy and Tauopathies

MALUCCI Giovanna (Leicester, United Kingdom)
Restoring protein synthesis rates for neuroprotection in neurodegenerative disease

MELKI Ronald (Gif-sur-Yvette)
Protein folding in vitro and conformational diseases

MORIMOTO Rick (Evanston, USA)
Reproduction and Aging: Two sides of Proteostasis Health

NOLLEN Ellen (Groningen, The Netherlands)
Cellular drivers of protein aggregation and toxicity

SERPELL Louise (Falmer, United Kingdom)
Unravelling amyloid toxicity: from structure to function

SPILLANTINI Maria Grazia (Cambridge, United Kingdom)
Proteinopathies: from iPSC to animal models

WEGMANN Susanne (Charlestown, USA)
TAU's toxicity and propagation

ZURZOLO Chiara (Paris, France)
Role of Tunneling Nanotubes (TNTs) in the spreading of prions and prion-like proteins in neurodegenerative diseases

 

 

Deadline for application: May 18, 2016

 

Registration fee (including board and lodging)

450 € for PhD students
650 € for other participants

 

Application for registration
The total number of participants is limited to 115 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should send:

- their curriculum vitae
- the list of their main publications for the 3 last years
- the abstract of their presentation:

The abstract must respect the following template:
- First line: title
- Second line: list of authors. Presenting author underlined
- Third line: author's addresses
- Fourth line: e-mail of the presenting author
Abstracts should be no longer than an A4 page and preferably be submitted in Times New Roman, font size 11 pts. No figures.".doc" file format.

to the Chairperson of the conference (luc.buee@inserm.fr) and to the secretary of the conferences (nathalie.babic@sb-roscoff.fr) before the deadline. After it, the organizers will select the participants. Except in some particular cases approved by the Chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.

 

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