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  Home > 2017 Conference series > Actin and microtubule cytoskeleton: bridging scales from single molecules to tissues

Actin and microtubule cytoskeleton: bridging scales from single molecules to tissues

 French version

Roscoff (Brittany), France, May 8-12, 2017


Deadline for application: February 1st, 2017


Chairperson: Thomas SURREY     

The Francis Crick Institute,1 Midland Road, London NW1 1AT, United Kingdom
Phone: +44 (0)203796 2044


Vice-chairperson: Laurent BLANCHOIN

Institute of Life Sciences Research and Technologies (iRTSV), Department of Plant and Cellular Physiology, CEA Grenoble, 17 rue des Martyrs, 38054 Grenoble cedex 9, France
Phone: +33 (0)4 38 78 32 90


This is the second Jacques Monod Conference focussing on the latest research on different types of cytoskeleton. Actin filaments and microtubules are the major cytoskeletal polymers in eukaryotic cells. As non-equilibrium polymers, they self-assemble and disassemble in a regulated and coordinated fashion and self-organise into dynamic higher order structures with complex functionalities in essential processes, such as cell polarisation, cell migration, cell division, and other morphogenetic processes important for cell differentiation. In bacteria, distantly related cytoskeletal proteins also coordinate cellular functions requiring the action of filaments. How complex functionalities emerge from the collective behaviour of the components of the cytoskeleton is a major open question in biology. Answering this important question will require the combined expertise from several disciplines. Several recent methodological developments in structural biology (cryo-EM, single particle analysis, tomography), biophysics (single molecule and super-resolution imaging) and cell biology (optogenetics and genome editing) have tremendously accelerated progress in several areas of actin and microtubule cytoskeleton research. At this conference, a multi-scale view of the cytoskeleton will be presented, including latest results on integrated actin/microtubule functions, cytoskeleton-membrane/boundary interactions and diversity of cytoskeletal arrangements between different cell types and cells in different species.

Invited speakers
(provisional titles)


ALUSHIN Gregory (Bethesda, USA)
Cytoskeletal structural plasticity in force generation and mechanosensation

ARNAL Isabelle (Grenoble, France)
Rôles of tau and APC in microtubule organization

BALASUBRAMANIAN Mohan (Warwick, United Kingdom)
Cytokinesis in vitro and in vivo

BAUSCH Andreas (München, Germany)
Shape remodelling: active cytoskeletal vesicles

BEAR James (Chapel Hill, USA)
Arp2/3-based actin dynamics in directional migration and metastasis

BROUHARD Gary (Quebec, Canada)
Microtubule quaternary structure and nucleation

CARTER Andrew (Cambridge, United Kingdom)
Structural insights into dynein/dynactin transport

DOGTEROM Marileen (Delft, Netherlands)
Building minimal mitotic spindles in artificial confinement

FAIX Jan (Hannover, Germany)
Characterization of an novel and exceptionally potent actin assembly factor from a human pathogen

GOODE Bruce (Waltham, USA)
Coordination of growing microtubule plus ends and actin assembly

HASHIMOTO Takashi (Ikoma, Japan)
Microtubule-mediated stress responses in plants

HEALD Rebecca (Berkeley, USA)
Mechanisms of mitosis and size control in Xenopus

JEGOU Antoine (Paris, France)
Regulation of actin bundle assembly by mechanics, biochemistry and architecture

KAPITEIN Lukas (Utrecht, Netherlands)
Navigating the cytoskeleton: novel tools to dissect and direct intracellular transport

KOVAR David (Chicago, USA)
Self-organization of functionally distinct actin filament networks

LECUIT Thomas (Marseille, France)
Biomechanics of cell and tissue morphogenesis

LENZ Martin (Orsay, France)
Extensile actomyosin?

LOOSE Martin (Klosterneuburg, Austria)
Self-organization of the bacterial cell division machinery

MOGILNER Alex (New York, USA)
Scaling of sizes and distances in multi-nucleated cells

MÜLLER-REICHERT Thomas (Dresden, Germany)
Three-dimensional reconstruction of spindle architecture in C. elegans

PETRY Sabine (Princeton, USA)
Molecular mechanism of a microtubule nucleation pathway

PIEL Matthieu (Paris, France)
At the front, at the back and in the middle: the whereabouts of actin during cell migration

POLLARD Thomas D. (Yale, USA) Keynote
Actin dynamics in live cells at high spatial and temporal resolution

SIXT Michael (Klosterneuburg, Austria)
Structure-function of lamellipodial actin

STEINMETZ Michel (Villigen, Switzerland)
Mechanisms of tubulin interacting ligands

SYKES Cecile (Paris, France)
Cell tension generated by acto-myosin and studied with controlled biomimetic systems

TERRET Marie-Emilie (Paris, France)
F-actin mechanics orchestrate the geometry of cell division in acentriolar oocytes and embryos

THERY Manuel (Paris, France)
Actin and microtubule fight for the centrosome

TOLIC Iva (Zagreb, Croatia)
Forces in the mitotic spindle

TRAN Phong (Paris, France)
Bipolar spindle formation without motors

WASTENEYS Geoffrey (Vancouver, Canada)
Motors and MAPs drive the growth and shrinkage of microtubule plus ends


Deadline for application: February 1st, 2017


Registration fee (including board and lodging)

500 € for PhD students
700 € for other participants


Application for registration
The total number of participants is limited to 115 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should send:

- their curriculum vitae
- the list of their main publications for the 3 last years
- the abstract of their presentation:

The abstract must respect the following template:
- First line: title
- Second line: list of authors. Presenting author underlined
- Third line: author's addresses
- Fourth line: e-mail of the presenting author
Abstracts should be no longer than an A4 page and preferably be submitted in Times New Roman, font size 11 pts. No figures. ".doc" file format.

Please indicate whether your abstract should be considered for an oral presentation.

to the Chairperson of the conference ( and to the secretary of the conferences ( before the deadline. After it, the organizers will select the participants. Except in some particular cases approved by the Chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.


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