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  Home > 2018 Conference series > Modeling cell fate

Modeling cell fate


 French version

Roscoff (Brittany), France, November 19-23, 2018


Deadline for application: August 26, 2018


Chairperson: Laure BALLY-CUIF

Department of Developmental and Stem Cell Biology, Institut Pasteur and CNRS UMR3738, 25 rue du Dr Roux, 75015 Paris France
Phone: +33 (0)1 4061 3202


Vice-chairperson: Claude DESPLAN

Dept. Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York NY 10003, USA
Phone: +1 212 998 8218


Developmental biology has become an interdisciplinary field, addressing the question of cell fate in the contexts of gene regulation but also of cellular history, cell geometries, the mechanical properties of cells and tissues, emerging population rules, and the 4D space-time dynamics of each cell and its environment. As a result, progress in the field is now tightly linked with advances in biophysics, mathematical modelling and quantitative approaches measuring these various components of cell and tissue behaviour.
Recognizing these needs, the 2018 edition of the CJM Developmental Biology series, entitled “Modeling Cell Fate”, will place emphasis on characterizing and modelling the dynamics of cell fate choices. In the context of living organisms, we will progress through all analysis scales, from the biophysics, biochemistry and 4D organization of the intracellular space and single molecules to the morphogenesis and functional assembly of the tissue. The conference program will be divided into 5 thematic sessions: (1) Emerging properties of cell populations; (2) Cell interactions sculpting tissues; (3) Physical properties of cells; (4) Cell lineages in embryos and tissues; (5) Stochasticity of gene regulation in patterning. Speakers will include experimentalists but also theorists of the mathematics and physics fields
Overall, this scientific program will address the most emerging issues of developmental biology questions and concepts, in an interdisciplinary manner, and will serve as a forum for scientists of biology, physics and mathematics backgrounds to interact.

Invited speakers
(provisional titles)


Geneviève ALMOUZNI (Paris, France)
From chromatin states to cell fate

Alexander AULEHLA (Heidelberg, Germany)
Oscillatory signaling dynamics controlling mesoderm patterning

Laure BALLY-CUIF (Paris, France)
Neural stem cell pools homeostasis in the adult vertebrate brain

Allison BARDIN (Paris, France)
Adult stem cell genome regulation

Dominique BERGMANN (Stanford, USA)
Chance and necessity in the plant epidermis

Florence BESSE (Nice, France)
Compartmentalizing the regulation of gene expression in neurons

Sarah BRAY (Cambridge, United Kingdom)
Decoding the Notch response

Claire CHAZAUD (Clermont, France)
Cell lineage differentiation in the inner cell mass of the blastocyst

Enrico COEN (Norwich, United Kingdom)
Polarity, growth and the generation of tissue shape

Michèle CROZATIER (Toulouse, France)
Hematopoiesis and control by the microenvironment:analyses in Drosophila

Claude DESPLAN (New York, USA)
Coordination of neurogenesis between brain regions to generate retinotopy

Alain GORIELY (Oxford, United Kingdom)
The mechanics of neuronal morphogenesis

Thomas GREGOR (Princeton, USA)
Enhancer dynamics: bringing the genome to life

Laura JOHNSTON (New York, USA)
Tissue ecology: sensing and responding to differences in cellular fitness during growth

Frank JÜLICHER (Dresden, Germany)
Shaping a fly wing

Ryoichiro KAGEYAMA (Kyoto, Japon)
Oscillatory control of neural stem cells

Bill KEYES (Illkirch, France)
Investigating the function of cellular senescence in development and regeneration

Thomas LECUIT (Marseille, France)
Self-organization and regulation of cell mechanics during tissue morphogenesis

Andy OATES (London, United Kingdom)
Timers and clocks in embryonic segmentation

Ewa PALUCH (London, United Kingdom)
Cell shape and mechanics during fate changes in mouse embryonic stem cells

Nancy PAPALOPULU (Manchester, United Kingdom)
The role of pulsatile expression dynamics in regulating stem cell quiescence and plasticity

Catherine RABOUILLE (Utrecht, The Netherlands)
Formation of stress assemblies in cells and tissues

Jody ROSENBLATT (Salt Lake City, USA)
Epithelial extrusion and its misregulation in disease

François SCHWEISGUTH (Paris, France)
Cell fate patterning

Benjamin SIMONS (Cambridge, United Kingdom)
A unifying theory of branching morphogenesis

Claudio STERN (London, United Kingdom)
Dissecting the molecular complexity of neural induction

Julien VERMOT (Strasbourg, France)
Mechanical forces and cell responses in the cardiovascular system

JP VINCENT (London, United Kingdom)
Growth regulation by patterning signals

Magdalena ZERNICKA-GOETZ (Cambridge, United Kingdom)
Modeling development of the mammalian embryo with stem cells in vitro

Pat O'FARRELL (San Francisco, USA)
Onset of histone modifications at the MBT that immediately specify segmental fate


Deadline for application: August 26, 2018


Registration fee (including board and lodging)
460 € for PhD students
650 € for other participants


Application for registration
The total number of participants is limited to 115 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should deposit online before the deadline:

- their curriculum vitae
- the proof of their student status
- the list of their main publications for the 3 last years
- the abstract of their presentation:

The abstract must respect the following template: TemplateResumeFile
- First line: title
- Second line: list of authors. Presenting author underlined
- Third line: author's addresses
- Fourth line: e-mail of the presenting author
Abstracts should be no longer than an A4 page and preferably be submitted in Times New Roman, font size 10 pts. No figures. ".docx" file format.

After the deadline, the organizers will select the participants. Except in some particular cases approved by the Chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.

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