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  Home > 2018 Conference series > Retrograde signalling from endosymbiotic organelles

Retrograde signalling from endosymbiotic organelles

 French version

Roscoff (Brittany), France, October 15-19, 2018

 

Deadline for application : July 4, 2018

 

Chairperson: Thomas Pfannschmidt

Laboratoire de Physiologie Cellulaire & Végétale, UMR5168 CNRS / Univ. Grenoble Alpes / CEA / UMR1417 INRA, Institut de Biosciences et Biotechnologies de Grenoble, 17 rue des Martyrs, 38054 Grenoble cedex 9, France
Phone: +33 (0)4 76 78 05 69
Email: Thomas.Pfannschmidt@univ-grenoble-alpes.fr

 

Vice-chairpersons: Matthew Terry

Biological Sciences, University of Southampton, Life Sciences Building 85, Highfield Campus, Southampton SO17 1BJ, United Kingdom
Phone: +44 (0)23 80592030
Email: mjt@soton.ac.uk

 

Retrograde signalling from endosymbiotic organelles - It has become increasingly apparent that the endosymbiotic organelles of eukaryotic cells, plastids, including chloroplasts, and mitochondria, are highly integrated into cellular signalling networks. In both heterotrophic and autotrophic organisms, plastids and/or mitochondria require extensive organelle-to-nucleus communication in order to establish a coordinated expression of their own genomes with the nuclear genome that encodes the majority of the components of these organelles. This goal is achieved by the use of a variety of signals that inform the rest of the cell about the number and developmental status of the organelles and their reaction to changing external environments. Such signals have been identified in both photosynthetic and non-photosynthetic eukaryotes (known as retrograde signalling and retrograde response, respectively) and, therefore, appear to be universal mechanisms acting in eukaryotes of all Kingdoms. In particular, chloroplasts and mitochondria both harbour crucial redox reactions that are the basis of eukaryotic life and are therefore particularly susceptible to stress from the environment, which they signal to the rest of the cell. These signals are crucial for cell survival, life span and environmental adjustment, and include quality control and targeted degradation of dysfunctional organelles, metabolic adjustments, developmental signalling as well as induction of apoptosis. The functional similarities between retrograde signaling pathways in autotrophic and non-autotrophic organisms are striking, suggesting the existence of common signalling mechanisms. In this meeting, we will bring together researchers from a wide range of experimental systems to try for the first time to build a bridge between these different research areas. By discussing commonalities and differences in the signaling mechanisms, we hope to develop our understanding of retrograde signaling as a general signaling mechanism in eukaryotic cells.

 

Invited speakers
(provisional titles)

 

Tessa BURCH-SMITH (University of Tennessee, USA)
A role for chloroplast signaling in controlling intercellular communication

Olga CORTI (Université Paris 6, France)
Mitochondrial quality control regulated by PINK1 and Parkin and its role in the retrograde response from mitochondria

Katie DEHESH (University of California, USA)
Role of the plastidial retrograde signal methyl erythritol cyclopyrophosphate (MEcPP) in plant stress signalling and development

Karl-Josef DIETZ (Bielefeld University, Germany)
Retrograde control of cytosolic translation

Anne-Marie DUCHÊNE (Université de Strasbourg, France)
The role of RNAs in mitochondria/nucleus interaction

Iris FINKEMEIER (University of Muenster, Germany)
Role of mitochondria in retrograde signalling

Bernhard GRIMM (Humboldt-University Berlin, Germany)
Role of tetrapyrroles in retrograde signaling and plant development

Michel HAVAUX (CNRS, Marseille, France)
Role of ROS and carotenoid derivatives during retrograde signalling under stress conditions

Tatjana KLEINE (Ludwig-Maximilians-Universität München, Germany)
The role of plastid translation in plastid retrograde signalling and its interaction with mitochondria

Anja KRIEGER-LISZKAY (CEA Saclay, Gif-sur-Yvette, France)
Redox and ROS regulation in the coordination of mitochondria and plastids during photosynthesis

Karin KRUPINSKA (Christian-Albrecht-University of Kiel, Germany)
Role of the Whirly1 protein in retrograde signalling and nucleoid structure of plastids

Roland LILL (Philipps-Universität Marburg, Germany)
The essential roles of mitochondria in the maturation of cytosolic and nuclear iron-sulfur proteins and in intracellular iron metabolism

Enrique LOPEZ-JUEZ (Royal Holloway, University of London, United Kingdom)
Interaction of light and plastid signals during early events of chloroplast biogenesis

Elena MONTE (Center for Research in Agricultural Genomics, Barcelona, Spain)
Interaction of plastid retrograde and phytochrome signalling pathways during plant development

Phil MULLINEAUX (University of Essex, United Kingdom)
Photosynthesis-dependent H2O2 transfer from chloroplasts to nuclei provides a high-light signalling mechanism

Thomas PFANNSCHMIDT (University Grenoble Alpes, France)
Retrograde signalling mediated by photosynthetic redox signals and plastid transcription

Barry POGSON (Australian National University, Australia)
Stress signalling via the metabolite 3′-phosphoadenosine 5′-phosphate (PAPS)

Hélène PUCCIO (Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France)
The retrograde response from mitochondria during iron-sulfur cluster and coenzyme Q10 biosynthesis

Pedro M. QUIROS (Universidad de Oviedo, Spain)
Retrograde response from mitochondria to the nucleus during homeostasis and stress

Norbert ROLLAND (University Grenoble Alpes, France)
Exchange of metabolites and metabolic signals between plastids and cytosol and novel pathways of protein sorting towards plastids using the QORH protein as model

Nicolas ROUHIER (Université de Lorraine, France)
The maturation of Fe-S proteins in chloroplasts and mitochondria

Uwe SCHLATTNER (University Grenoble Alpes, France)
Functional impairment of mitochondrial NME4 triggers a metastasis-like phenotype: a role for retrograde signaling?

Asa STRAND (Umeå University, Sweden)
Plastid signals during plant development

Matthew J. TERRY (University of Southampton, United Kingdom)
Role of singlet oxygen and tetrapyrroles in retrograde signaling from chloroplasts

Michel B. TOLEDANO (CEA-Saclay, Gif-sur-Yvette, France)
ROS and redox signalling in the retrograde response from mitochondria to the nucleus

Frank VAN BREUSEGEM (VIB, Gent, Belgium)
Cell signalling functions of reactive oxygen species and inter-organellar communication between plastids and mitochondria

Jim WHELAN (La Trobe University, Australia)
Retrograde signalling from Arabidopsis mitochondria

 

Deadline for application: July 4, 2018

 

Registration fee (including board and lodging)

450 € for PhD students
675 € for other participants

 

Application for registration
The total number of participants is limited to 115 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should send:

- their curriculum vitae
- the list of their main publications for the 3 last years
- the abstract of their presentation:

The abstract must respect the following template:
- First line: title
- Second line: list of authors. Presenting author underlined
- Third line: author's addresses
- Fourth line: e-mail of the presenting author
Abstracts should be no longer than an A4 page and preferably be submitted in Times New Roman, font size 11 pts. No figures. ".doc" file format.

to the Chairperson of the conference (Thomas.Pfannschmidt@univ-grenoble-alpes.fr) and to the secretary of the conferences (nathalie.babic@sb-roscoff.fr) before the deadline. After it, the organizers will select the participants. Except in some particular cases approved by the Chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.

 

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